Monday, Aug 7: 2:25 PM - 2:45 PM
Topic-Contributed Paper Session
Metro Toronto Convention Centre
In clinical studies there are huge numbers of laboratory parameters available that are measured at several visits for several treatment groups. The status quo for presenting laboratory data in clinical trials consists in generating large numbers of tables and data listings. Such tables and listings are required for submissions to health authorities. However, reviewing laboratory data presented in the form of tables and listings is a lengthy and tedious process. To enable efficient exploration of laboratory data we developed elaborator, a comprehensive and easy-to-use interactive browser-based application. The elaborator app comprises three analysis types for addressing different questions, for example about changes in laboratory values that frequently occur, treatment-related changes and changes beyond the normal ranges. This discussion will focus on the elaborator app that can be used to identify safety signals in a clinical trial as well as generating hypotheses that are further inspected with detailed analyses and possibly data from other sources.