The effect of smoking on peri-operative, post-operative, and overall survival after robotic assisted pulmonary resection
Presented During:
Saturday, May 6, 2023: 8:00AM - Tuesday, May 9, 2023: 11:45AM
Los Angeles Convention Center
Posted Room Name:
Outside of Room 408
Abstract No:
PS072
Submission Type:
Abstract Submission
Authors:
Jobelle Baldonado (1), Emma Wong (2), Taina Romeus (2), Jacques-Pierre Fontaine (3), Eric Toloza (3)
Institutions:
(1) H. Lee Moffitt Cancer Center and Research Institute, Tampa, United States, (2) University of South Florida, Tampa, FL, (3) Moffitt Cancer Center, Tampa, FL
Submitting Author:
Jobelle Baldonado
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H. Lee Moffitt Cancer Center and Research Institute
H. Lee Moffitt Cancer Center and Research Institute
Co-Author(s):
Emma Wong
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University of South Florida
University of South Florida
Taina Romeus
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University of South Florida
University of South Florida
Jacques-Pierre Fontaine
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Moffitt Cancer Center
Moffitt Cancer Center
*Eric Toloza
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Moffitt Cancer Center
Moffitt Cancer Center
Presenting Author:
Jobelle Baldonado
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H. Lee Moffitt Cancer Center and Research Institute
H. Lee Moffitt Cancer Center and Research Institute
Abstract:
Objective: To analyze the effects of smoking on perioperative and postoperative outcomes of robotic-assisted lobectomy and segmentectomy in an NCI-designated cancer center.
Methods: Data was analyzed from 1,420 consecutive patients who underwent robotic-assisted segmentectomy (n=1,370) and lobectomy (n=50) performed by three different surgeons over a 12-year period. The perioperative, postoperative, and overall survival outcomes were compared between smoking patients (n=297) and non-smoking patients (n=1,123). The perioperative outcomes that were compared include estimated blood loss (cc), surgical duration (min), chest tube days, and hospital length of stay (LOS). Postoperative complications, 30-day mortality, and overall survival (OS) were also compared. Perioperative outcomes were compared between smoking and non-smoking groups using the student t-test. 5-year OS was compared using the log-rank test.
Results: There was a significant difference in preoperative FEV1% (p<0.0001) between smoking and non-smoking groups. Non-smoking patients had a greater mean FEV.1%. The smoking group had a significantly larger proportion of patients with chronic obstructive pulmonary disease compared to the non-smoking group (p<0.0001). The most significant differences in perioperative outcomes were chest tube duration (p<0.001) and total surgical duration (p=0.047), in which smoking patients experienced both longer chest tube duration and surgical duration. The remaining perioperative outcomes, 30-day mortality, and overall survival did not show any significant differences between both groups. The most significant differences in postoperative complications were prolonged air leak (p=0.025) and pneumonia (p=0.02), with smoking patients having a higher rate of incidence for both. Prolonged air leak was the most common complication in both smoking (67/297, 22.6%) and non-smoking patients (184/1,123, 16.4%). Pneumonia was the second most common complication in smoking patients (21/297, 7.1%).
Conclusion: The results indicate that smoking not only has a negative impact on preoperative FEV1%, but also on perioperative outcomes and postoperative complications in patients undergoing robotic-assisted pulmonary resections.
Methods: Data was analyzed from 1,420 consecutive patients who underwent robotic-assisted segmentectomy (n=1,370) and lobectomy (n=50) performed by three different surgeons over a 12-year period. The perioperative, postoperative, and overall survival outcomes were compared between smoking patients (n=297) and non-smoking patients (n=1,123). The perioperative outcomes that were compared include estimated blood loss (cc), surgical duration (min), chest tube days, and hospital length of stay (LOS). Postoperative complications, 30-day mortality, and overall survival (OS) were also compared. Perioperative outcomes were compared between smoking and non-smoking groups using the student t-test. 5-year OS was compared using the log-rank test.
Results: There was a significant difference in preoperative FEV1% (p<0.0001) between smoking and non-smoking groups. Non-smoking patients had a greater mean FEV.1%. The smoking group had a significantly larger proportion of patients with chronic obstructive pulmonary disease compared to the non-smoking group (p<0.0001). The most significant differences in perioperative outcomes were chest tube duration (p<0.001) and total surgical duration (p=0.047), in which smoking patients experienced both longer chest tube duration and surgical duration. The remaining perioperative outcomes, 30-day mortality, and overall survival did not show any significant differences between both groups. The most significant differences in postoperative complications were prolonged air leak (p=0.025) and pneumonia (p=0.02), with smoking patients having a higher rate of incidence for both. Prolonged air leak was the most common complication in both smoking (67/297, 22.6%) and non-smoking patients (184/1,123, 16.4%). Pneumonia was the second most common complication in smoking patients (21/297, 7.1%).
Conclusion: The results indicate that smoking not only has a negative impact on preoperative FEV1%, but also on perioperative outcomes and postoperative complications in patients undergoing robotic-assisted pulmonary resections.
Categories:
Lung Cancer
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