MP51. Recurrent Prosthetic Valve Tricuspid Valve Regurgitation Due to Carcinoid; Open or Interventional Approach?

Barbara Robinson Poster Presenter
Mayo
Lake Barrington, IL 
United States
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Dr. Barbara Robinson MD,MS, is an independent board-certified cardiothoracic surgeon trained at Stanford, Mayo Clinic  and Harvard with great patient satisfaction, HCAP scores,low O/E scores, and many unsolicited patient satisfaction letters of thanks; teaching recognition and awards , research awards from the Mayo Clinic, Harvard, STS and AATS, presentations at AATS, STS, ACS,  AHA , WIM,  Chest,  ISMICS, ISHLT.

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Description

INTRODUCTION
We report a case of severe bioprosthetic carcinoid tricuspid valve regurgitation(TR), rapid degeneration of a pericardial tricuspid valve prosthesis performed robotically and rereplacement via sternotomy with a mechanical valve. Bioprosthetic tricuspid valve destruction may occur with persistent carcinoid disease. With combined cardiac and hepatic disease, addressing the cardiac component is favored first. Severe TR is an indication for tricuspid valve replacement(TVR).

With combined cardiac and hepatic disease, addressing the cardiac component is favored. The choice of prosthetic TVR remains controversial with some groups favoring mechanical, others biological. Mechanical valve may obviate risk of bioprosthetic valve deterioration if persistent hepatic carcinoid disease is present. Tissue valve options include bioprosthesis or percutaneous choices.
We report a case of rapid degeneration by carcinoid of a pericardial tricuspid valve prosthesis performed robotically and rereplacement with a mechanical valve via sternotomy.

METHODS
A 45-year-old man with primary terminal ileal carcinoid tumor, hepatic metastases, elevated chromogranin levels, previously treated with chemotherapy presented with dyspnea, a pansystolic murmur, jugular venous distention, hepatomegaly, ascites, and peripheral edema. Original preoperative TEE seen by the cardiothoracic surgery attending of the initial native stenotic and regurgitant tricuspid valve secondary to carcinoid disease showed massive TR with leaflet sclerosis and tethered, retracted chords (Figure 1). The patient did not desire a mechanical prosthesis initially with concern for possible hepatic reintervention.
RESULTS
He initially underwent a right thoracic robot-assisted #29 Magna Ease bovine pericardial TVR. Nine months later he developed severe tricuspid bioprosthesis insufficiency.
At median sternotomy reoperation, fibrotic tissues surrounded the tricuspid annulus.
The thickened, immobile and retracted pericardial bioprosthesis was difficult to extirpate and was replaced via median sternotomy with a 27-mm St. Jude mechanical prosthesis.He is well postoperatively.
CONCLUSION
We illustrate a case of bovine pericardial bioprosthesis destruction with carcinoid.
Options for subsequent bioprosthesis degeneration from persistent carcinoid have not been thoroughly
Historically, the morbidity and mortality of TVR have been higher in carcinoid.
Percutaneous options should be considered.

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