P130. Expanding Indications of Rapid Deployment Aortic Valve Replacement: Five-year Outcomes from A Single-center Experience

Sheraton Times Square 

Objective: Rapid deployment aortic valve replacement (RD[AVR]) has been widely used for the treatment of aortic valve stenosis. However, there is limited evidence on the use of the RD valve in aortic valve diseases other than aortic stenosis. This study evaluated the 5-year outcomes of RDAVR for various aortic valve diseases in a single center.
Methods: Overall 344 patients who underwent AVR using INTUITY valve in our institution between 2016 and 2023 were included. Early clinical outcomes, mid-term clinical outcomes and hemodynamic outcomes from early postoperative period to postoperative 5 years were also investigated. Median follow-up duration was 28.6 months (maximum 86.4 months).
Results: Mean age was 68.9 ± 9.8 years, and 46.2% were female. There were 176 bicuspid valves (51.2%), 20 pure aortic regurgitations (5.8%), and 4 infective endocarditis (1.2%). Isolated RDAVR was performed in 90 patients (26.2%), and concomitant procedures were performed in 254 patients (73.8%), including aorta surgery (48.8%), mitral valve surgery (20.3%), arrhythmia surgery (9.0%), tricuspid valve surgery (7.0%), and coronary artery bypass grafting (5.5%). Operative mortality was observed in 11 patients (3.2%), and permanent pacemaker implantation was required in 5 patients (1.5%) during the early postoperative period. The 1-year and 5-year survival rates were 94.2% and 84.0%, respectively, and freedom from aortic valve-related events were 89.0% and 77.9% in 1 year and 5 years, respectively. No deterioration of valve hemodynamics in every size of the prostheses was observed up to 5-year echocardiographic evaluation. Mean pressure gradients of the prostheses were 9.9 ± 4.3 mmHg and 9.4 ± 3.8 mmHg at 1 year and 5 years, respectively.
Conclusions: The RD valve can serve as a reliable bioprosthesis for both isolated and concomitant AVRs for various aortic valve diseases, including bicuspid valve, pure aortic regurgitation, and infective endocarditis. Excellent clinical and hemodynamic results would be guaranteed up to 5 years.

Authors
SEON YONG BAE (1), Kyung Hwan Kim (1), Suk Ho Sohn (1), Yongwoo Chung (1), Yoonjin Kang (1), Ji Seong Kim (1), Jae Woong Choi (1)
Institutions
(1) Seoul National University Hospital, Seoul, Seoul

PODS will be on display in the exhibit hall for the duration of the meeting during exhibit hall hours. PODS will also be available for viewing on the meeting website. There is no formal presentation associated with your POD, but we encourage you to visit the PODS area during breaks to connect with those viewing.