Search Abstracts

579 Matches found.
Proposal No Title
109 Crystal Structures of Large-Volume Commercial Pharmaceuticals
113 A Catalog of Human Gut Microbial Sulfatases Reveals Structural Features Essential for Endobiotic Processing
117 Bringing the Real World to a Crystallography Lab – A Quality Management Framework
120 SAXS studies of X-ray induced disulfide bond damage: Engineering high-resolution insight into a low resolution technique
126 Structural characterization of three distinct beta-glucuronidases from the gut commensal bacterium Roseburia hominis
127 X-ray diffraction reveals the mechanical load tolerance of mammalian neuronal tissues in traumatically induced injury
128 Structural Studies of TraG, the Conjugative Entry Exclusion Protein from the F-plasmid
129 Advanced Methodology and Measurements of Material and Mechanical Properties of Heart Valves Under Dynamic Strain
130 Molecular Storytelling for Structural Biology Outreach and Education
132 Insights into the molecular mechanism of metal transport by NRAMP family transporters
138 Inviting Others to Life in Reciprocal Space
139 An X-ray Free Electron Laser (XFEL) Science Education Model Designed for Large Centers and Its Application To Individual Laboratories
140 Macromolecular X-ray Crystallography in the Undergraduate Curriculum
142 Structural analysis of human intestinal alpha-glucosydases: Sucrase-isomaltase and maltase-glucoamylase.
148 When the unusual is the normal: making non-standard structural studies routine.
150 Exploring Twinning in the CSD
152 A novel form of allosteric regulation in an ancient enzyme: mapping GTP’s effect on ribonucleotide reductase with SAXS and crystallography
155 Further evidence supporting the allosteric regulation of PEPCK by anions.
157 One-Pot Synthesis of Heterometallic Copper-Manganese Complexes with Polyfunctional Imidoyl Amidine Ligands
158 High Impact Small Molecule Crystallography Skills Development Through Local Undergraduate Curriculum and Regional Workshops and Schools
159 Development of a model protein for HIV Tat structural study and drug development
162 Crystallographic Description of Ordered Toroidal Moments
164 Infusible Nuclear Fuel Synthesis beyond 25,000 °C for Far Deep Cosmic-Space Explorations
165 Zero Ramachandran outliers does not guarantee a “good” model
166 Towards Engineering the Polymorphs of Cocrystals
168 Magnetic and Structural Properties of Thiophosphates Li2MP2S6 where M = Fe and Co
170 BioXTAS RAW 2.0: The latest in SAXS data analysis
172 BioCAT beamline enables high quality equilibrium and time resolved biological solution SAXS
174 Sub-100 Microsecond Time Resolved SAXS at BioCAT
175 Electron Diffraction for Characterization of Nanocrystal Materials: Beyond the Crystal Structure
179 The Rigaku HyPix-Arc 150: The First Curved Photon Counting Detector
180 Malaria parasite translocon structure and mechanism of effector export
181 Applications of Microfluidic Mixers for Time-Resolved SAXS and Crystallography Experiments
184 Uranyl Dicyanoaurate Coordination Polymers Through the Dimensions
188 Exploring mechanisms of insulin-degrading enzyme activation and localization in the degradation of amyloid beta and insulin.
189 Compression rate dependence of the α to ω phase transition in titanium
193 Development of an Alternative Approach to Time-Resolved X-ray Crystallography
194 Structural chemistry of CuCN network solids with N-alkylethanolamine cation guests
195 Structures of MHC-I/Tapasin and MHC-I/TAPBPR Describe the Mechanism of Peptide Loading Antigen Presentation
196 Crystallography in the High School Classroom.
197 Structure and effector-binding analysis of a PreQ1-III riboswitch suggests a fold that is tolerant to binding pocket mutations.
199 Structural Basis for Strand Transfer Inhibitor Binding to HIV Intasomes
202 Cryogenic methods for biological small-angle x-ray scattering
203 Bayesian refinement of full profile diffraction patterns for uncertainty quantification
204 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase, a Key Target for Novel Antibacterial Development against Acinetobacter baumannii and Klebsiella pneumoniae
205 Crystallization of Heme Dioxygenases IDO and TDO Facilitate Structure-Based Design of Cancer Immunology Therapeutics
210 Don’t be afraid of modulated structures
212 Protein Data Bank in the Time of Coronavirus: How open-access 3D structures are enabling research and development in fundamental biology, biomedicine, biotechnology, and drug discovery as we confront the global SARS-CoV-2 pandemic.
213 Crystal structure of a bacterial Dicer that is ideal for the preparation of heterogeneous siRNA cocktails
214 Structure of the RECK CC domain, an evolutionary anomaly
216 RNA Duplex Recognition and Unwinding by DEAD-Box Helicase DDX3X
217 Time-resolved serial synchrotron crystallography for the functional characterization of proteins
218 Can 3D Electron Diffraction Provide Accurate Atomic Structures of Metal-Organic Frameworks?
219 Crystallization of novel polyglycine hydrolases found in the fungal response against plant defensive chitinases
220 X-ray Lite: A 1-Credit Pass/Fail Crystallography Course
222 Observation of nine-fold coordinated amorphous TiO2 at high pressure
225 The Order of the Fullerene
226 Dissecting the specificity of a TCR-mimic antibody targeting TP53 R175H mutation-derived neoantigen
230 Structural Study of LmFPPS Bisphosphonate Inhibitors
231 Native SAD data collection using microbeam at NSLSII
232 Nanobodies for isoform-specific study of voltage-gated sodium channels (Navs)
237 Evaluating crystallographic likelihood functions using numerical quadratures.
238 Hyper-Molecules: High Dimensional Maps of Molecular Conformations
239 Astex's journey of fragment-based drug discovery using cryo-EM
240 Controlling π-Stacking Interactions in a Series of Novel Heteroacene Derivatives
242 Teaching a Large Scale Crystallography School with Zoom Webinar
243 Ai Testing
244 CryoEM at Sanofi
245 Interactive Python Programs for Crystallography
247 Structural basis of ribosomal RNA transcription regulation
248 Atomistic ensembles of proteins and soft matter complexes from MD simulations and solution scattering data
249 Psychiatric risk peptide of DISC1 inhibits kinase GSK3β, Structural investigation using crystallography
251 RCSB PDB Next-generation Data Delivery and Search Services
252 HIV-1 CD4 binding site antibody N49P6 mimics CD4 in its quaternary interactions with the HIV-1 Envelope trimer.
255 Conformational switching of FMN and THF riboswitches
256 Structural insights into the recognition of mono- and di-acetylated histones by the ATAD2B bromodomain
257 How Low Can You Go? Exploring the Lower Limit of Crystal Size on a Home X-ray Source
258 The pymolsnips library to aid the writing of PyMOL scripts
259 Cryo-EM Reveals Active Site Coordination Within a Multienzyme pre-rRNA Processing Complex
260 An Introduction to the Gold Standard for Macromolecular Crystallography Diffraction Data
261 Study on structure, electrical and dielectric properties of pure and Sr-doped LaCoO3 for chemical sensor application.
262 X-ray fiber diffraction as a tool to study Nemaline Myopathy, a debilitating muscle disease
263 Macromolecular X-ray crystallography: soon to be a road less traveled?
264 Structural Basis for the tight binding inhibition of E coli. CTP Synthase Inhibition by Gemcitabine and its analogues
265 Structure of MlaFEDB lipid transporter reveals an ABC exporter fold and two bound phospholipids
271 The SHAPES Program for the Reconstruction of Protein Envelopes from X-ray Solution Scattering Data
272 Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase
273 Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase
274 Comprehensive strategy for quick determination of protein structures
276 MyD88 TIR domain signalosome interactions revealed by MicroED
277 Photocrystallographic studies of novel nickel (II) nitro complex supplemented by IR spectroscopy and multi-temperature XRD experiments
278 Recent advances in serial electron crystallography
279 Lessons learned from using the MiTeGen In Situ-1™ Crystallization Plate for microgravity protein crystallization
280 LabJack-like crystal structures of halogenated 2-phenylbenzimidazoles – are they isostructural?
281 The National School on Neutron and X-ray scattering (NX school) at Argonne and Oak Ridge National Lab
282 Partially Ordered Sets in Crystallography
283 Tracking solvent dynamics during carbonic anhydrase catalysis
284 Implementing Best Practices At The National Center For CryoEM Access And Training
285 Through-grid wicking enables high-speed cryoEM specimen preparation
286 Maximizing the value of cryoEM in drug discovery
287 High resolution cryo-EM structure of the EspA filament from EPEC: revealing the mechanism of effector translocation in the type 3 secretion system
288 High resolution cryo-EM structure of the EspA filament from EPEC: revealing the mechanism of effector translocation in the type 3 secretion system
289 Targeting Fe-S Protein to Fight Neglected Tropical Diseases
290 Cryo-EM and protein-protein docking reveal myosin loop 4 contacts actin and tropomyosin on thin filaments
291 Time-resolved serial femtosecond crystallography of the early intermediates in the isopenicillin N synthase reaction with ACV and O2
292 Towards Synergy of Macromolecular and Small Molecule Crystallography
293 A Portable Fixed-Target Sample Delivery System for in-situ Serial Crystallography
294 Pushing the Limits of Microfocus X-Ray Sealed Tube Sources for Biological and Chemical Crystallography
295 What's shaking? Molecular-dynamics simulations of X-ray diffraction from crystalline proteins.
296 Structural basis for the target specificity of actin histidine methyltransferase SETD3
297 Serial Electron Diffraction for Proteins and Small Molecules
298 Patient derived Fab structures suggest mechanism by which affinity maturation promotes autoantibody recognition of MuSK in the autoimmune disease myasthenia gravis
299 CryoDiscovery (TM): A machine learning platform for automated Cryogenic electron microscopy class average selection
300 CryoDRGN: a tool for reconstructing highly heterogeneous structural ensembles from cryo-electron micrographs
302 Small Molecule Microcrystal Electron Diffraction (MicroED) for the Pharmaceutical Industry
303 Determining Atomic Structures from Digitally Defined Regions of Nanocrystals
304 Structural Basis of the Interaction Between Ubiquitin Specific Protease 7 and Enhancer of Zeste Homolog 2
305 Broad HIV neutralization by a vaccine-induced cow antibody
306 Correction of the allosteric site of E. coli D-3-phosphoglycerate dehydrogenase
307 High-Pressure Structural and Equation of State Study of Atacamite, a Copper Hydroxychloride Mineral
308 New methods to capture insoluble, unstable titanium (IV) species in single-crystal form.
309 Structure of the human respiratory syncytial virus M2-1 protein in complex with a short positive-sense gene-end RNA
310 Toledo Crystallization Box: Microgravity Crystallization of Perdeuterated S. typhimurium Tryptophan Synthase for Neutron Diffraction
311 Undecided
313 Understanding the stoichiometric diversity and reactions of cocrystals through experimental and computational studies
314 Bacterial pseudokinase catalyzes protein polyglutamylation to inhibit the SidE-family ubiquitin ligases
315 Summer schools for magnetic crystallography and neutron diffraction
316 A bacterial surface layer protein exploits multistep crystallization for rapid self-assembly
317 How CRY Regulates the Clock: Structural Studies of a Dynamic Mammalian Circadian Complex
318 Structure of V-ATPase from mammalian brain
319 Translating hands-on activities to virtual resources for broader scientific engagement
322 Investigation of ATP-induced global motions of the human DNA mismatch repair sensor complex using time-lapse crystallography 
323 Structural characterization of different TRPA1 inhibitors
324 A Battleground with no Neutral Ground: Twitter for Scientists
325 Capturing Reaction Intermediates of the Water Oxidation Reaction In Photosystem II
326 Complementing high resolution structure methods with small angle X-ray scattering data.
327 Time-resolving biomolecular motions on length scales from single Å to Rg
329 Synthesis and characterization of metastable, crystalline st12 germanium
330 Structures of a dimodular nonribosomal peptide synthetase reveal conformational flexibility.
332 Real-time pressure-temperature reaction studies of biological systems using small-angle neutron scattering technique.
333 Direct detection of coupled proton and electron transfers in human manganese superoxide dismutase
334 Toledo Crystallization Box: Microgravity Crystallization of Perdeuterated S. typhimurium Tryptophan Synthase for Neutron Diffraction
335 HP-Bio: High Pressure BioSAXS for Deep Life and Extreme Biophysics
336 A Consensus Method to Prepare Crystal Structures in the Protein Data Bank for Downstream Applications
337 Single-particle cryo-EM studies of ERp44-ERAP1 and ERp44-ERAP2 reveal their ER-retention mechanism and structural dynamics involved
338 Incorporating HT-SAXS into Drug Discovery Pipelines
339 Finding Nearest Neighbors in Crystallography with NearTree
340 Understanding High-Pressure Formation of Topologically Non-trivial Intermetallic Compounds via In-Situ X-ray Diffraction
341 Cool structures from event-based single crystal neutron diffraction
342 Enhancing Protein Crystallization Screening Results Using Engineered Nucleation Features
343 Computationally directed discovery of bismuth based binary intermetallic materials
344 REGALS: data analysis at the SAS frontier
345 Toledo Crystallization Box: Microgravity Crystallization of Perdeuterated S. typhimurium Tryptophan Synthase for Neutron Diffraction
346 Structure of the Fiber Core of Orb2A, A Functional Amyloid, Revealed by Micro-electron Diffraction
347 Structure of an ALS/MSP-related D290V-mutation-containing hexapeptide in hnRNPA2 low-complexity domain reveals differences from its corresponding wild type peptide
348 Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20
350 A cryoEM and microED pipeline for the pharmaceutical and biotechnology industry
351 The Crystallization Transformations Sequence as Ice is Compressed at Low Temperature: Avoidance of Amorphization
352 The ISOTILT program for discovering cooperative rigid-unit modes (RUMs) in crystalline solids
353 Measurement of partial atomic charges by least-squares refinement of variable electron density crystallographic models.
354 Structural insights into enzymatic mechanism of methylenetetrahydrofolate reductase (MTHFR) from Sphingobium sp. SYK-6
356 Polymorph Evolution of Organic Molecules during Crystal Growth Studied by MicroED
357 Recent Developments SAXS using MetalJet X-ray Source
358 Utilizing Single-Crystal X-ray Diffraction to Determine Unusual Structural Trends within Group 15 Triamido Complexes
359 SYNTHESIS AND STRUCTURAL CHARACTERIZATION OF LaMnO3+δ AND La0.8AE0.2MnO3+δ (AE=Ca, Sr, Ba) PEROVSKITES FOR CATALYTIC OXIDATION OF VOLATILE ORGANIC COMPOUNDS
360 High Pressure Study on Novel Quantum Materials
362 _
363 Understanding c-di-GMP Signaling Specificity in Pseudomonas aeruginosa Pel-dependent Biofilms
365 Superconducting Superhydrides: Synthesis, Structure and Stability
366 Reinvestigation of the crystal structure of bis(3-aminopyridinium) tetrachloridocuprate(II)
367 Industrial CryoEM: reasons why and examples of impact
368 chameleon: Next Generation Sample Preparation for Cryo-EM
370 Mail-in and remote access for solution scattering at the LiX beamline
371 Evaluation of covalent bond density in molecular crystals using simplified virtual scattering centers: inorganic and complex compounds
372 Improved MicroED structures by cryo-FIB milling
373 MicroED on lipidic cubic phase embedded crystals
374 A cross-phase reaction coordinate in the formation of a mononuclear copper(II) orotate complex
375 Materializing Rival Ground States in the Barlowite Family of Kagome Magnets
376 Synthetic investigation on structure-property relationships in the Ca2-xMnxTi2O6 quadruple perovskite system
379 The SER-CAT Virtual Beamline: Providing light when YOU need it in your home lab
385 Discovery of an inhibitor of succinyl-CoA synthetase
386 A High Pressure Macromolecular Crystallography Capability Developed at CHESS
387 Structure-activity relationship analysis of mosquito glutathione S-transferase Noppera-bo and its inhibitors for insecticide development
388 Bimetallic platinum-based complexes: syntheses and synchrotron X-ray radiation structural studies
389 Bis(S-(-)-1-phenylethylammonium) tetrabromidocuprate(II): another step in the sequential breakdown of the A2CuX4 layer perovskite structure
390 Upconversion Enhancement via Functionalization of Plasmonic Nanoparticles
393 The crystal structure of gallic acid decarboxylase from Arxula adeninivorans
395 Crystal and Solution structures of Proliferating Cell Nuclear Antigen from Crenarchaeon Aeropyrum pernix
396 Investigation of Disease-causing Mutations in Sucrase-Isomaltase
397 Optimization of crystallization conditions for PfActII in complex with fragmin F1 domain
398 Structural basis for bisphosphonate-mediated inhibition of Leishmania major FPPS
399 Access modes to the highly automated BioSAXS beamline P12 of EMBL Hamburg
401 1,2-Cyclobutanecarboxylates Synthesized Using Photoreaction and Esterification
402 Targeting Protein Farnesyltransferase for Development of Antifungal Therapeutics
403 MicroED for small molecule and natural product research
404 B-factor analysis suggests that L-lysine and R, R-bisLysine allosterically inhibit Cj.DHDPS Enzyme by decreasing its protein dynamics
405 Structural study of phenylperimidines with potential applications as corrosion inhibitors
406 Optimal Box Size and Mask Diameter based on Defocus Distribution for Single Particle Cryo-EM
407 High-pressure Neutron Diffraction on WAND2in a Paris-Edinburgh Press
408 Structural study by X-ray diffraction of iron (III) complexes
409 Structural Studies of Manganese(III) Complex with Spin-Crossover and Thermochromic Properties
410 Using crystallographic models to experimentally measure partial atomic charges with comparison to quantum calculations
411 Direct and Simple Experimental Crystallographic Method to Calculate Partial Charges with Atomistic Correspondence to ab-initio Methods
412 Structural basis of Neisserial lactoferrin binding protein B function
413 DECOR: The Database of Educational Crystallographic Online Resources, Updates and Prospectus
414 Synthesis, Crystal Structures and Biomedical Application of Ferrocene-Hormone Complexes
415 FAD
417 test
418 Stanford-SLAC Cryo-EM Center
419 Electronic Structure and Site Dynamics in Copper Doped Tutton Salts
420 Application of neural networks for small angle scattering data analysis
421 The 1.9Å structure of PA5083 – a 116 residue protein with 1 ordered sulfur - determined by Native-SAD using in-house data and phenix.autobuild recycling.
422 Stanford-SLAC Cryo-EM Center
423 The 1.9Å structure of PA5083 – a 116 residue protein with 1 ordered sulfur - determined by Native-SAD using in-house data and phenix.autobuild recycling.
424 Structural basis of recognition of SARS-CoV-2 by neutralizing antibodies isolated from convalescent patients
425 Make MicroED an efficient tool for ultrahigh-resolution structural determination∠
426 Ternary alkali metal zinc antimonides and bismuthides: hydride synthesis and in-situ X-ray diffraction study
427 Structural insights into the feline coronavirus drug GC376, which inhibits the main protease of SARS-CoV-2 and blocks virus replication
430 Remote Opener: Breaking Barriers to Crystallization Using Remote Crystal Growth Screening and Imaging
431 If I had a trillion dollars
432 High-resolution crystal structures of recombinant wild type and selenomethione labeled bovine trypsin (S195A) mutant reveals no electron density for three surface loops that includes the C191 - C220 disulfide.
433 Structure-based Design of Prefusion-stabilized SARS-CoV-2 Spikes
434 Science at a distance: the CHESS experience
436 Advancing Structure-Based Drug Design: IMCA-CAT Responds to Emerging Needs of the Pharmaceutical Industry
437 Socially-distanced Crystallography in the time of COVID: Remote capabilities at SSRL
438 Microcrystal electron crystallographic analysis of organic solid solution (mixed crystal)
439 Online Crystallography: Fully Automated, Remote Controlled Protein-to-Structure Pipelines
440 Effects of chameleon dispense-to-plunge speed on particle concentration, complex formation, and final resolution: A case study using a bacterial ribonucleotide reductase
441 Structure and effector-binding analysis of a PreQ1-III riboswitch suggests a fold that is tolerant to binding pocket mutations.
442 Crystallography of SARS-CoV-2 Non-structural Proteins
443 A complete data processing workflow for in situ structure determination with cryo-electron tomography
444 Neural network particle picking and denoising in cryoEM with Topaz.
445 New developments in Scipion 3.0: consolidating the project as a collaborative software framework.
446 Single-particle cryo-EM at atomic resolution
447 Neural network particle picking and denoising in cryoEM with Topaz
449 Structural disorder and conformational flexibility in single particle cryo-EM
450 Understanding the evolution of SARS-CoV-2 non-structural protein 15 (Nsp15) in three dimensions (3D)
451 Mapping COVID-19 Mutations in 3D: How SARS-CoV-2 has evolved during the first 6 months of the global pandemic
452 Structural Analysis of Severe Acute Respiratory Syndrome Coronavirus-2 Proteins: Exploring Mutations in Nsp13
453 Delving Into COVID-19 “Seams”: Examining the Structural Fabric of SARS-CoV-2
455 Long range magnetic cooperativity through extended structural motifs? Introducing intermolecular - interactions into [3×3] Mn(II)9 and Cu(II)9 grids.
457 Optimal Box Size and Mask Diameter based on Defocus Distribution for Single Particle Cryo-EM
458 Lattice dynamics of antimony under pressure
459 High-resolution in situ imaging of biological samples with Warp and M
460 Crowdsourcing inhibitor discovery against the SARS-CoV-2 main protease
461 Protein Allostery
469 Crystal Structures of Large-Volume Commercial Pharmaceuticals
472 Structural relationships between human transcriptional coactivators TFIID and SAGA
473 Integrating Chemical Crystallography into Undergraduate Laboratories: A Remotely Conducted Discovery Based Molecular Structure Determination Lab Module
474 Structural Characterization of a Hydroxyproline Dehydratase from C. difficile
475 Structurally investigating a niche pathway for chemical reversal of proline hydroxylation in the pathogen C. difficile
476 Diffraction and scattering studies using high brightness Excillum MetalJet X-ray sources
478 From integrative structural biology to cell biology
479 Methods to Trap High-Temperature Conformations of Proteins using Fast Cooling
480 Structures of Synthetic Nanobodies in Complex with SARS-CoV-2 Spike or Receptor-Binding Domain Provide Insights for Developing Therapeutics and Vaccines
481 Direct visualization of SARS-CoV-2 main protease electrostatics using neutron crystallography
482 Structural Analysis of a Zirconium Based Hydrogen Storage Material
484 Crystal Structure of a Zirconium Based Hydrogen Storage Material
486 Evaluation of the electrostatic potential, electric field and electric field gradient from the aspherical pseudoatom model in an infinite crystal.
487 Deploying high-throughput protein crystallography-based drug discovery platforms to establish a structure-based drug discovery system for SARS-CoV-2 proteins
488 AAA
490 First structures as undergraduate and graduate student
492 Anecdotal Lessons from the 1990’s
493 Taking away PAIN: Enabling new structures of the Nav1.7 sodium channel by cryo-EM
494 Structure-Based Drug Design of Bcl-XL Selective Inhibitors
497 THE NATIONAL CENTER FOR CRYOEM ACCESS AND TRAINING : NATIONWIDE ACCESS TO CRYOEM TECHNOLOGY AND CURRICULA
498 The Journey of Macromolecular Crystallography in Pharmaceutical Discovery Research at Abbvie and BMS.
499 Four lessons from my very early days in crystallography: The lasting impact of a few selected ‘first structures’ on my path in science.
502 Investigating Photoreception, and Bio-catalysis using Time-resolved Serial Femtosecond Crystallography
503 Variable Temperature Polymorphism of 2-benzoyl-N,N-diethylbenzamide
504 First observation of aromatic bond density: a ‘forgotten’ paper by Rosalind E. Franklin
505 Conceptual Design of a Small- and Wide-angle Neutron Scattering Diffractometer/Spectrometer for the Second Target Station of the SNS: Centaur
506 Integrating Crystallography in Undergraduate Lab Experiences
507 Extending the structural space of quasiracemic materials
508 Water Soluble Picolamidine Metal Complexes
509 Largest Problem: Getting a crystal and what is it worth to the researcher to have the 3D crystalline structure? Academic and Industrial Aspects.
510 Warmer, deeper, wider: New developments at MacCHESS
511 Snapshots and ensembles of BTK and cIAP1 protein degrader ternary complexes
512 How to discover new solids containing alkali metals: predictive screening, facile synthesis and in situ studies
514 Lessons in Translational Non-Crystallographic Symmetry: Solving the Crystal Structure of a Putative Protease from Gemella haemolyans
515 Introducing the XtaLAB Synergy Flow
516 A blended learning approach for a crystallography-based undergraduate practical [under COVID-19 restrictions]
517 Structural basis of redox sensing by a cyanobacterial transcription regulator
518 Rosalind Franklin and the Structure of Graphitic Carbons
519 Probing the Local Atomic Structure of High-Entropy Oxides
520 Experimental Realization of Transverse Ising model on kagome and triangular lattice antiferromagnets
522 Probing Magnetic Structure of Thin-film Magnetic Materials Using a Resonant X-ray Magnetic Diffraction
523 Nematicity in a local-moment iron chalcogenide
524 Ligand-induced global conformational changes in TBP-associated factor 1 (TAF1) tandem bromodomains – a novel strategy for targeting the TAF1.
527 Salt Effects on Li-ion Exchange Kinetics and Activation Energies – Systematic In Situ Synchrotron Diffraction Studies
528 Darkrooms, paper tape, punch cards and grease pencils: Doing crystallography at Caltech in the early 1970s
529 Cannabidiol: A natural product structure in the mid-1970’s. Weissenberg photos, four-circle diffractometry, direct methods, and more
530 Fusion to the TELSAM Protein Polymer Dramatically Improves the Speed of Target Protein Crystallization by Stabilizing Weak Crystal Contacts
534 Instrumentation and applications of simultaneous SAXS/WAXS at the LiX beamline
535 TELSAM accelerates crystallization of fused target proteins by stabilizing weak crystal contacts
536 Diffraction in the Context of the National Science Foundation (NSF)
537 Probing Structural Attributes for Li-Argyrodite as a Fast Ion Conductor using Neutron Powder Diffraction
538 Elucidating lactate oxidase enzyme-biomarker lactate interactions by SAXS, crystallography and X-ray footprinting for developing a real-time stress biosensor.
539 Factors of Atomic Electron Scattering (FAES): A resource for Gaussian parameterization of integral ionic, fractionally charged, and neutral electron scattering factors
540 Rosalind Franklin’s pivotal research on coal, DNA and viruses.
542 Isoreticulation of Zwitterionic Metal-Organic Frameworks for Electrochromic Applications
543 How the Coupled Spin, Orbital and Lattice Degrees of Freedom Can Cause Happiness or Distress in Asymmetric Magnetic Exchange Interaction, and Why It Matters for Microelectronic Applications
545 Innovations in Electric Field-Stimulated X-Ray Crystallography
546 CryoEM Structures of Macromolecules
547 Structural Insights into Outer Membrane Protein Biogenesis in Pathogenic Neisseria
548 Direct detection of coupled proton and electron transfers in human manganese superoxide dismutase
549 The Use of Blender and SketchFab to Create and Share Teaching Tools for Crystallography
552 Jumping in the deep end: 1970s structural challenges and their impact for a career in crystallography teaching and research
553 Molecular Engineering of Single-crystal Optical Actuators
554 Neutron PDF study of catalysts and battery materials: current status and future opportunities
555 The important role of dynamics in the function and misfunction of molecular machines
556 Revealing exotic magnetic states through machine learning assisted modeling of neutron diffuse scattering data
557 Avoiding Sample Collisions with Puck Visualization for MX
559 CryoDiscovery (TM): A Machine Learning Platform for Automated Cryo-electron Microscopy 2D Class Selection
560 Exploring aliovalent substitutions in the lithium halide superionic conductor Li3-xIn1-xZrxCl6 (0 ≤ x ≤ 0.5)
561 Cryo-EM structures of inhibitory antibodies complexed with Arginase1 provide insight into mechanism of action.
563 Crystal Structure and Characterization of Human Heavy-Chain Only Antibodies Reveals a Novel, Stable Dimeric Structure Similar to Monoclonal Antibodies
564 Histone H2B ubiquitination in transcription regulation
566 Innovation by Evolution: Bringing New Chemistry to Life
568 Structure based design of degraders.
569 The Many Moods of the 3-Aminopyridinium Chlorocuprate(II) System
570 A Global consortium, next-generation SARS-CoV-2 antibody therapeutics and stabilized spike
571 Solid-solid phase transition in adenine riboswitch crystals driven by large conformational changes induced by ligand
573 Single crystal diffraction beyond three dimensions: Dynamic structural responses of hydrogen-bonded materials using time filtering of event-based neutron TOF Laue diffraction
574 The Changing Economics of an Academic Structural Biology Core Facility
575 Structural Science Awakens – with a splash of water to the (inter)face
576 What it Takes for a Successful Mix-and-Inject Serial Crystallography Experiment: From a Sample Preparation and Sample Delivery Perspective
577 Pervasive approximate symmetry in organic P1 structures
578 On the contribution of substrate flexibility to define Methionine adenosyltransferase specificity
579 Revealing structural dynamics of proteins with time-resolved x-ray liquidography
580 Challenging the limits of detection technology
581 From lab to synchrotron and back: could better, faster and newer also be more economical?
582 Emap2sec+: Detecting Protein and DNA/RNA Structures in Cryo-EM Maps of Intermediate Resolution Using Deep Learning
583 Using the ALEX nylon mesh holder for time-resolved serial crystallography: successes and drawbacks.
584 A simple pressure-assisted method for MicroED specimen preparation
585 Reverse Monte Carlo refinement of single crystal diffuse neutron scattering and correlated magnetic disorder with program rmc-discord
586 Electronic Structure-Property Relations of Photochromic MOFs from the Cambridge Crystallographic Structural Database
587 Building a crystallographic instrument company - planning and serendipity
588 Dissecting the selectivity of antibodies recognising neoantigen-MHC-I complexes derived from oncogenes
589 How to collect better data? Longer exposure times versus higher redundancy
590 Evolving charge density wave and band structure control in topological semimetals LnSbxTe2-x-δ(Ln = Ce, Nd, Gd)
591 Macromolecular machines at energized membranes
592 Fully fluorinated Pd(F6acac) complexes: polymorphism and fluorine-fluorine interactions.
593 Sample Centering Using Google Cloud Platform's AutoML Vision.
596 Visualization of the constellation of protons in the product-inhibited state of human manganese superoxide dismutase
597 Assemblies of DNA grafted nanoparticles deciphered by SAXS
598 MAINMAST: De Novo Protein Structure Modeling for cryo-EM Maps Assisted by Structure Feature Detection by Deep Learning
599 Engaging diverse students with Crystallography Research
600 Scaling up: processing XFEL data at kilohertz speeds using cctbx.xfel
601 Toward elucidating the mechanism of lytic polysaccharide monooxygenases: Chemical insights from X-ray and neutron crystallography
603 Optimizing the conditions for GGDPS crystal growth
605 The TELSAM Protein Polymer significantly Improves the Speed of Crystallization of target proteins
607 Mutation to second sphere residue in peptidylglycine α-hydroxylating monooxygenase (PHM) reveals role of hydrogen-bonding network
608 Structure-Guided Design of Cryptococcus neoformans Protein Farnesyltransferase Inhibitors with Antifungal Activity
609 Using (3+1)D Space to Investigate a Modulated Superstructure Mystery
610 Classification of tissue variations in X-ray scanning microdiffraction from thin sections of human brain
611 Adventures in structural chemistry education: techniques for teaching crystallography virtually
614 Magnetic vortices in a square lattice revealed by local magnetic susceptibilities and neutron diffuse scattering
615 Structural analysis of fibrillar polymorphs in AD (Alzheimer Disease) brain tissue and Pair distribution function of associated fibrils
616 The ideal crystal for structural biology
617 New Structural Insights into the Function of the Catalytically Active Human Taspase1
620 High Entropy Alloys local structure study by Reversed Monte Carlo method
621 Discovery and investigation of a naturally evolved fractal-like protein complex
622 The ID29 upgrade project: a new serial crystallography beamline for time resolved studies at ESRF-EBS
623 Development of a Large Area Fast Readout HPC Detector
624 La2O3-type structure magnetic topological candidates
625 Elucidating Ionic Mobility in Multivalent Spinel Oxides
626 Towards the structural analysis of an F plasmid protein, TraW
627 Developing novel tools to guide the discovery of new cell-permeable, on-target anti-infective compounds.
628 Protein Crystallography & PUIs
629 Understanding the structure of (1-x)BaZr0.2Ti0.8O3 - (x)Ba0.7Ca0.3TiO3 based lead-free piezoelectric materials
631 Bispecifics and CAR T cells that target intracellular cancer driver mutations
632 Nano-scale Structure and Composition of Mixed Micelles Revealed by Small-Angle Neutron Scattering (SANS) and Molecular Dynamics (MD)
633 Learning in the Lockdown: Free Online CryoEM School
634 Visualization of biomolecular structures by WAXS and MD
635 Probing structural dynamics of biomolecules in solution at high resolution via time-resolved small- and wide-angle x-ray scattering
636 Decoding hidden structural information in solution wide-angle X-ray scattering (WAXS): from ensemble modeling to machine learning
637 Intramolecular Radical formation-induced chemical stability of novel ZW-MOFs
639 Time-resolved x-ray scattering studies on the BioCARS beam line at the APS: the nuts and bolts of pushing the limits achievable at a synchrotron facility
640 Beamline Science – The Video Game: How Reinforcement Learning and Artificial Intelligence are Changing Operations at Large-Scale User Facilities
641 Switchable Rashba anisotropy in a layered hybrid organic–inorganic perovskite via hybrid improper ferroelectricity
643 Probing photoinduced protein function by time resolved X-ray scattering
644 What are the current limits on determination of protonation state using neutron MX?
645 Structural analysis of polymorphs of small organic molecules by 3D ED/MicroED
646 Mg2+ and Mn2+ coordinate Cap-0-RNA to position substrates for efficient 2´-O-methyl transfer by SARS-CoV-2 nsp16
647 Algebraic analysis of topological domain-interface defects in crystals
648 Discrete conformations of an enzyme are discernible via hierarchical clustering of X-ray diffraction intensities derived from multiple crystals
649 Photoreactivity and polymorphism of cinnamic acid revisited
650 The APS upgrade offering new opportunities for materials science
651 Neutron Diffractometer Concept(s) for the Second Target Station at the Spallation Neutron Source*
652 Structural, magnetic ordering process and the magnetic excitations in spinel FeMn2O4
653 High entropy multication rock salt oxides for lithium ion batteries
654 A comprehensive strategy for efficient generation of well-diffracting crystals
655 Running a non-profit shared core facility
656 Data and Diversity Driven Development of a Shotgun Crystallisation Screen using the Protein Data Bank
657 Solving protein structure using highly realistic diffraction photographs generated from MD trajectory of crystalline lysozyme
658 Interpretable Machine Learning of Volumnious Scattering data
659 Crystallography of Lithiated and Delithiated Transition Metal Phosphates and Thiophosphates
661 In situ grazing incidence total scattering: new in situ capabilities for pair distribution function analysis of thin films
662 Understanding Quantum Materials Under Extreme Sample Environments
663 Understanding conformational changes in MCM-family helicases through experimental structures and SVD-based metadata analysis´
665 Determine anisotropic g-tensor of rare-earth magnet using polarized neutron powder diffraction
666 Pushing the Boundaries in Crystallization Screening: Making Automated, User-accessible Crystallization Work
667 Materials on the nanoscale: Total scattering analysis for nanoparticle chemistry
668 Recognition of the Plasmodium spp. circumsporozoite protein by malaria inhibitory antibodies
669 Solving a structure as a goal vs. solving a structure as a tool. Learning crystallography along evolving times.
671 MnBi2Te4.nBi2Te3: a happy marriage of magnetism and topology
672 Ice in Biomolecular Crystallography
673 Progress towards developing an experimental platform for high-throughput CryoSAXS
675 Tuning the magnetism and band topology through antisite defects in Sb doped MnBi4Te7
677 POLO: A web interface for the rapid identification of crystals
679 Solution scattering and high-pressure biology
680 Introduction to "What can and can't we see"
681 SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity
682 Controlling the Morphology of Lipid Bicelles
683 Broken-helix antiferromagnetic order protecting a crystalline axion insulator phase and exotic surface states in EuIn2As2.
684 Approximate Lattice Similarity
685 Redox modulation on chloroplast ATP synthase
686 Tuning of disordered local structure in Prussian Blue analogues
687 The First X-ray Crystal Structures of 5,5,10,10-Tetrahalotricyclo[7.1.0.04,6]decanes
688 Small angle x-ray scattering of the intrinsic tenase complex bound to lipid nanodisc provides insight into intermolecular contacts between factors VIIIa/IXa
689 Historical notes on early neutron crystallography at the Oak Ridge Research Reactor
691 Structural and functional characterization of the glycosyltransferase PglA from Campylobacter concisus
692 Structural insight into the evolution of allostery
693 Structural Investigation of 4,4,8,8-Tetrahalotricyclo[5.1.0.03,5]octanes
694 Crystal Structure and Structure-Property Relationship of Halide Superionic Conductors as Solid Electrolyte for All-Solid-State Batteries
695 MqsA antitoxin degradation is regulated by zinc occupancy and oxidation
696 SERCAT-BCSB Collaboration During SER-CAT/APS Upgrade
697 X-ray Crystallography at a Small Canadian University – A Personal Perspective
698 Magnetic properties in new half-Heusler-type compound
699 Understanding Selective Propane/Ethane Gas Adsorption using Neutron Diffraction
700 Structural insight into dual function of Neisserial lactoferrin binding protein B
701 Small Molecule Microcrystal Electron Diffraction (MicroED) for the Pharmaceutical Industry – Lessons Learned from Examining Over Fifty Samples
702 Peptidoglycan binding by a pocket on the accessory NTF2-domain of Pgp2 directs helical cell shape of Campylobacter jejuni
704 Novel Iridates Single Crystals Grown under High Pressure
706 Meet the Family: Structural and Kinetic Comparisons of Representative PEPCKs
707 The High Pedagogic Value of Low Impact Publications
709 Integrated Resource for Reproducibility in Molecular Crystallography: experiences of the first five years
710 Literate programming with CCTBX and PyMOL in Jupyter notebooks
711 Singular value decomposition (SVD) of particle movements for motion analysis in cryoEM movies
712 Micro crystal electron diffraction of the peptide Gramicidin
713 Centers of Spatial and Time Inversion Symmetry in Magnetoelectric Crystalline Materials
714 Sample preparation technologies for serial synchrotron crystallography and single-particle cryo-EM
715 The Life and Times of the PDB Format - Looking Towards the Future with mmCIF
716 NSF’s ChemMatCARS - Advanced Crystallography Program A Dedicate Advanced Small Molecule Crystallography Beamline
717 Bicontinuous microemulsion (BμE) as a membrane-mimic to stabilize and enable structural studies of membrane proteins
718 Structures of Usutu SAAR-1776 virus: a comparison with known structures of mature flaviviruses
719 Correlates of successful structure solution in cryoEM single particle reconstruction (SPR)
720 Understanding Intermetallic Intergrowths and Reactivity: Chemical Pressure-Driven Epitaxy Between Domain Interfaces
721 Advanced data collection at FMX – the Frontier Microfocusing Macromolecular Crystallography Beamline at the National Synchrotron Light Source II
722 Scattering Signatures of Bond-Dependent Magnetic Interactions
723 Role of Crystallography in Pharmaceutical Solid Form Development
724 Adapting to varying resolutions in ISOLDE
725 Plug-and-play polymer microfluidic chips for hydrated, room-temperature fixed-target serial crystallography.
726 Structural Studies on Soft Matter Self-Assembly with Small-Angle X-ray Scattering
727 A large area photon counting X-ray detector with indirect conversion
728 Scanning mapping of biological tissues using scattering contrast
729 Rosalind Franklin, Still Guiding the Development of Carbon Based Materials
731 High energy upgrade of the Linac Coherent Light Source
732 Beam image-shift accelerated data acquisition for near-atomic resolution single-particle cryo-electron tomography
733 Charge-integrating hybrid pixel array detectors for x-ray science and electron microscopy
734 Metal-halide mediated radical generation and crystallization
735 A Video Demonstration of a Single Crystal X-Ray Determination of Sugar
737 Structural analysis of self-assembled block copolymer systems using small angle neutron and x-ray scattering techniques
738 Can We Do Research Without Taxpayer Funding?
739 Structure-Function Studies on Cereblon and the Implications for Novel Molecular Glue Discovery
740 Turning Up the Heat on Molecular Machines with Multi-Temperature and Temperature-Jump X-ray Scattering Experiments
741 Mapping atomic models back into cells - visual proteomics and in situ structure determination.
742 Interpretation of RNA cryo-EM maps of various resolutions
743 New developments in Time-of-Flight Neutron Detectors at Oak Ridge National Lab
744 Outcomes from EMDataResource Model Challenges
745 Molecular packing in double gyroid cubic phases revealed via resonant soft X-ray scattering
746 The Dynamic Interplay between Cell Membranes and Membrane Proteins
748 Crystallization Conditions in the Protein Data Bank
749 Polarized resonant soft X-ray scattering measurements in polymer-grafted nanoparticles
750 Crystallographic snapshots of TsrM, a cobalamin-dependent radical S-adenosylmethionine methylase
751 Fragments of stories
753 Porting Crystal Structure Data to Virtual Reality using CAD2VR
754 SMALL-ANGLE NEUTRON SCATTERING FOR INTEGRATIVE STRUCTURAL MODELING OF MEMBRANE PROTEINS IN CIRCULARIZED NANODISCS
755 Constraining Evolution ⇒ Avoiding Drug Resistance: Lessons from Viruses
756 Rosalind Franklin and her legacy in structural biology; the TMV chapter
758 Magnetic behavior of Cu-intercalated MnPSe3
759 Pushing the Boundaries: Creative methods for resolving conformational and compositional heterogeneity
760 PySeg in Scipion: making easier template-free detection and classification of membrane-bound complexes in cryo-electron tomograms.
762 Interrogating macromolecular complex assembly by systematically analyzing the composition of highly heterogeneous structural ensembles
763 Statistical estimation of spatially-resolved heterogeneity from cryo EM images
764 Introducing undergraduate students to single crystal X-ray diffraction through a course-based undergraduate research experience
765 Advances in modelling continuous heterogeneity from single particle cryo-EM data
766 Advances in heterogeneous reconstruction with cryoDRGN
767 MicroED: conception, practice and future opportunities
769 Scipion for tomography: An expansion of Scipion software framework towards integration, reproducibility and validation in cryo-electron tomography.
770 A Fab-ulous approach for solving structures of small membrane proteins using cryo-EM
771 XrayView: A teaching aid for X-ray crystallography
772 Trends in macromolecular structure data across 50 years of the PDB
773 Structural and dynamic basis for evolutionary bifurcations in enzyme families
774 Novel Solutions to Accelerate Cryo-EM Single Particle Analysis Sample Screening
775 Ternary PROTAC structures – necessary and sufficient?
777 Discovery and structural characterization of a VHL-mediated molecular glue degrader targeting cysteine dioxygenase
778 Microgravity crystallization for improving uniformity and homogeneity of crystals for time-resolved diffusive mixing XFEL experiments
782 BioMAX, a macromolecular crystallography facility at MAX IV
783 Low background serial crystallography experiments
784 Cryo-FIB Milling Improves MicroED Data and Structures
785 Neutron reflectometry of peripheral membrane proteins on biomimetic membranes: capabilities and examples
786 Reflections on Resolution and Revolution – the PDB and me
787 Ensemble epistasis: thermodynamic origins of non-additivity between mutations
788 RCSB Protein Data Bank: Integrated Searching and Efficient Access to Macromolecular Structure Data from the PDB Archive
789 Structural investigations into the avian MHC-I like protein YF1*7.1
790 Protein synchronization methods and considerations: light activation and rapid mixing
795 Protein folding computed from evolutionary information
796 Microcrystal Electron Diffraction for Molecular Design of Functional Non-Fullerene Acceptor Structures
797 MicroED with a direct electron detector
798 DIALS data processing for MicroED
799 MicroED application for GPCRs: structure of the human adenosine A2A receptor determined from a single nanocrystal in LCP
800 Structural Characterization of the Homeodomain Transcription Factor Gsx2 Bound to DNA
802 Dynamical refinement: The way to improved fit, accurate structure models and absolute structure from 3D ED data.
803 A simple technique to classify diffraction data from dynamic proteins according to individual polymorphs
804 Finding a way out of the Labyrinth: Degrader induced ternary complex modelling
805 Probing drug-protein interactions with MicroED
806 Evolved and evolving allosteric regulation in the biosynthesis of aromatic amino acids
807 Crystallographic Literacy – American Crystallographic Association
808 Rapid response to biomedical challenges and threats
810 A simple vapor-diffusion method enables protein crystallization inside the HARE serial crystallography chip
811 Discover: A Total Scattering Diffractometer for Materials Discovery at the SNS
813 Understanding the structural and functional details of Rv3716c, a hypothetical protein from Mycobacterium tuberculosis
814 Understanding the structural and functional details of Rv3716c, a hypothetical protein from Mycobacterium tuberculosis
815 Developments in Advanced Handling, Storage, Transport, and Tracking of Cryo-EM Samples
816 Structural Studies of the Conjugative Entry Exclusion Protein from the F and R100 Plasmids, TraG
817 Insights into Benzylisoquinoline Alkaloid Recognition Revealed by the 2.4 Å Crystal Structure of Codeionone Reductase
818 The next generation RCSB.org
819 Falcon 4 performance validation by single event analysis
820 Transitioning from a crystallographer to a structural biologist: Lessons learned
821 Rosalind Franklin and DNA
822 BioCAT beamline enables high quality equilibrium and time resolved biological solution SAXS
825 Structural and functional studies on Salmonella typhimurium pyridoxal kinase: the first structural evidence for the formation of Schiff base with the substrate
826 Structural basis of inhibition of the NUDIX family ORF141
827 Histone H4 acetyllysine coordination by ATAD2 bromodomain
829 fgdg
833 Operando oxidation and reduction neutron scattering studies on pristine and Pt-coated ceria nanorods
834 Structural insight into the neosubstrate selectivity of thalidomide metabolite
835 B4 Autocollect: a Fully Automated Data Collection and Data Processing Pipeline at the Berkeley Center for Structural Biology
836 Structural Comparison of Faecalibacterium prausnitzii α-glycosidases and Sucrase-Isomaltase
837 Cryo-EM reveals that MuB is an AAA+ regulator of transposition that distorts target DNA
838 Novel Cocrystallization of Apolipoprotein A-I with Butyric Acid
839 A structural investigation into an alpha-mannosidase found in Bacteroides thetaiotaomicron
840 Solid State Photoreactivity of Cinnamic Acid and Crotonic Acid Compared
841 Structural analysis of the Toc75 Potra domains from Pisum sativum
842 Unloxing the assembly and activation mechanism of Cre recombinase using cryo-EM
843 Modeling and machine learning tools to improve image processing in crystallization screening
844 The Future of Co-crystallisation: A New Workflow Based on AI Predictions, the Crystal16 Platform and Electron Diffraction
845 The role of BAM in mediating Fusobacterium nucleatum infection and pathogenesis
846 Crystal Structure of an Archaeal Dihydroorotase
847 What is a single cryo-EM image worth? A survey of high-resolution cryo-EM model system datasets
849 Two riboswitches with identical binding pockets and disparate RNA folds show different tolerances to equivalent mutations.
850 Structural insights into the mechanisms of substrate recognition and catalysis for the N-methyltransferases involved in benzylisoquinoline alkaloid metabolism
851 Structural biology response to biomedical threats
852 PDB-101 Video Challenge: Creating a Winning Entry
854 AutoMicroED: A semi-automated MicroED processing pipeline
855 A Compact Liquid Sample Automatic Handling System for Remote BioSAXS Operation
856 Structure and function of the respiratory syncytial virus polymerase
857 Understanding the short-range magnetic correlations in MnTe through magnetic pair distribution function analysis 
858 A Zwitterionic Metal-Organic Framework for the Capture and Release of Iodine
859 Using data mining to identify variations within the proteases of Coronaviridae
860 Biochemical analysis and review of the active site evolution of SARS-CoV-2 and other coronaviruses.
861 Bioinformatics and 3D Structural Analysis of the Coronavirus Main Protease Active Site
862 Hybrid-Pixel Detection and Software Automation Streamlining Electron Diffraction Experiments
863 Coronaviruses are a threat to the health of the global community. Prior to the COVID-19 global pandemic caused by SARS-CoV-2, severe acute respiratory syndrome (SARS-CoV) and Middle East respiratory syndrome (MERS-CoV) were coronaviruses that made the species jump to infect humans. In SARS-CoV-2, papain-like proteases (PLpro) participate in cleaving the polyproteins and liberating non-structural proteins. The non-structural proteins attach to each other and create a replication transcription complex which is used for viral replication. Targeting and disrupting coronavirus proteins with drugs is one strategy for stopping future outbreaks. Studying active site residues that are highly conserved between many variants will help in developing broadly effective inhibitors. We want to be able to identify or create a drug that will work against as many coronaviruses as possible, particularly for variants that differ in the chemical character of their active sites. In order to analyze the acti
864 Understanding the active site of the SARS-CoV-2 papain-like protease (PLPro)
865 On the Completeness of Three-Dimensional Electron Diffraction Data for Structural Analysis of Metal-Organic Frameworks
867 Improving data quality for 3D electron diffraction (3DED) by Gatan Image Filter
869 Electron cryo-microscopy at 100 and 200 kV: from screening to structures   
870 Structure of RNA-dependent RNA Polymerase 2 (RDR2) and its implications for double-stranded RNA synthesis in gene silencing 
871 The electron diffractometer: A dedicated user-friendly device for electron crystallography experiments
872 Design and Characterization of Rare Earth Metal-Based Zwitterionic Metal-Organic Frameworks
873 Pressure-induced reentrance of ferroelectricity in a molecular magnet
874 Extraordinary Structures of Orphan Methyltransferases with Their Substrate DNA
875 Synergy-ED: A new electron diffractometer for microED
876 A glimpse at the Balch-Olmstead fullerene legacy
878 Zirconium Hydroxide: Towards Facile Room-Temperature Synthesis of Zr-based Metal-Organic Frameworks
879 Growing protein crystals under different conditions
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