Search Abstracts

262 Matches found.
Proposal No Title
109 Crystal Structures of Large-Volume Commercial Pharmaceuticals
113 A Catalog of Human Gut Microbial Sulfatases Reveals Structural Features Essential for Endobiotic Processing
117 Bringing the Real World to a Crystallography Lab – A Quality Management Framework
120 SAXS studies of X-ray induced disulfide bond damage: Engineering high-resolution insight into a low resolution technique
126 Structural characterization of three distinct beta-glucuronidases from the gut commensal bacterium Roseburia hominis
127 X-ray diffraction reveals the mechanical load tolerance of mammalian neuronal tissues in traumatically induced injury
128 Structural Studies of TraG, the Conjugative Entry Exclusion Protein from the F-plasmid
129 Advanced Methodology and Measurements of Material and Mechanical Properties of Heart Valves Under Dynamic Strain
130 Molecular Storytelling for Structural Biology Outreach and Education
132 Insights into the molecular mechanism of metal transport by NRAMP family transporters
138 Inviting Others to Life in Reciprocal Space
139 An X-ray Free Electron Laser (XFEL) Science Education Model Designed for Large Centers and Its Application To Individual Laboratories
140 Macromolecular X-ray Crystallography in the Undergraduate Curriculum
142 Structural analysis of human intestinal alpha-glucosydases: Sucrase-isomaltase and maltase-glucoamylase.
148 When the unusual is the normal: making non-standard structural studies routine.
150 Exploring Twinning in the CSD
152 A novel form of allosteric regulation in an ancient enzyme: mapping GTP’s effect on ribonucleotide reductase with SAXS and crystallography
155 Further evidence supporting the allosteric regulation of PEPCK by anions.
157 One-Pot Synthesis of Heterometallic Copper-Manganese Complexes with Polyfunctional Imidoyl Amidine Ligands
158 High Impact Small Molecule Crystallography Skills Development Through Local Undergraduate Curriculum and Regional Workshops and Schools
159 Development of a model protein for HIV Tat structural study and drug development
162 Crystallographic Description of Ordered Toroidal Moments
164 Infusible Nuclear Fuel Synthesis beyond 25,000 °C for Far Deep Cosmic-Space Explorations
165 Zero Ramachandran outliers does not guarantee a “good” model
166 Towards Engineering the Polymorphs of Cocrystals
168 Magnetic and Structural Properties of Thiophosphates Li2MP2S6 where M = Fe and Co
170 BioXTAS RAW 2.0: The latest in SAXS data analysis
172 BioCAT beamline enables high quality equilibrium and time resolved biological solution SAXS
174 Sub-100 Microsecond Time Resolved SAXS at BioCAT
175 Electron Diffraction for Characterization of Nanocrystal Materials: Beyond the Crystal Structure
179 The Rigaku HyPix-Arc 150: The First Curved Photon Counting Detector
180 Malaria parasite translocon structure and mechanism of effector export
181 Applications of Microfluidic Mixers for Time-Resolved SAXS and Crystallography Experiments
184 Uranyl Dicyanoaurate Coordination Polymers Through the Dimensions
188 Exploring mechanisms of insulin-degrading enzyme activation and localization in the degradation of amyloid beta and insulin.
189 Compression rate dependence of the α to ω phase transition in titanium
193 Development of an Alternative Approach to Time-Resolved X-ray Crystallography
194 Structural chemistry of CuCN network solids with N-alkylethanolamine cation guests
195 Structures of MHC-I/Tapasin and MHC-I/TAPBPR Describe the Mechanism of Peptide Loading Antigen Presentation
196 Crystallography in the High School Classroom.
197 Structure and effector-binding analysis of a PreQ1-III riboswitch suggests a fold that is tolerant to binding pocket mutations.
199 Structural Basis for Strand Transfer Inhibitor Binding to HIV Intasomes
202 Cryogenic methods for biological small-angle x-ray scattering
203 Bayesian refinement of full profile diffraction patterns for uncertainty quantification
204 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase, a Key Target for Novel Antibacterial Development against Acinetobacter baumannii and Klebsiella pneumoniae
205 Crystallization of Heme Dioxygenases IDO and TDO Facilitate Structure-Based Design of Cancer Immunology Therapeutics
210 Don’t be afraid of modulated structures
212 Protein Data Bank in the Time of Coronavirus: How open-access 3D structures are enabling research and development in fundamental biology, biomedicine, biotechnology, and drug discovery as we confront the global SARS-CoV-2 pandemic.
213 Crystal structure of a bacterial Dicer that is ideal for the preparation of heterogeneous siRNA cocktails
214 Structure of the RECK CC domain, an evolutionary anomaly
216 RNA Duplex Recognition and Unwinding by DEAD-Box Helicase DDX3X
217 Time-resolved serial synchrotron crystallography for the functional characterization of proteins
218 Can 3D Electron Diffraction Provide Accurate Atomic Structures of Metal-Organic Frameworks?
219 Crystallization of novel polyglycine hydrolases found in the fungal response against plant defensive chitinases
220 X-ray Lite: A 1-Credit Pass/Fail Crystallography Course
222 Observation of nine-fold coordinated amorphous TiO2 at high pressure
225 The Order of the Fullerene
226 Dissecting the specificity of a TCR-mimic antibody targeting TP53 R175H mutation-derived neoantigen
230 Structural Study of LmFPPS Bisphosphonate Inhibitors
231 Native SAD data collection using microbeam at NSLSII
232 Nanobodies for isoform-specific study of voltage-gated sodium channels (Navs)
237 Evaluating crystallographic likelihood functions using numerical quadratures.
238 Hyper-Molecules: High Dimensional Maps of Molecular Conformations
239 Astex's journey of fragment-based drug discovery using cryo-EM
240 Controlling π-Stacking Interactions in a Series of Novel Heteroacene Derivatives
242 Teaching a Large Scale Crystallography School with Zoom Webinar
243 Ai Testing
244 CryoEM at Sanofi
245 Interactive Python Programs for Crystallography
247 Structural basis of ribosomal RNA transcription regulation
248 Atomistic ensembles of proteins and soft matter complexes from MD simulations and solution scattering data
249 Psychiatric risk peptide of DISC1 inhibits kinase GSK3β, Structural investigation using crystallography
251 RCSB PDB Next-generation Data Delivery and Search Services
252 HIV-1 CD4 binding site antibody N49P6 mimics CD4 in its quaternary interactions with the HIV-1 Envelope trimer.
255 Conformational switching of FMN and THF riboswitches
256 Structural insights into the recognition of mono- and di-acetylated histones by the ATAD2B bromodomain
257 How Low Can You Go? Exploring the Lower Limit of Crystal Size on a Home X-ray Source
258 The pymolsnips library to aid the writing of PyMOL scripts
259 Cryo-EM Reveals Active Site Coordination Within a Multienzyme pre-rRNA Processing Complex
260 An Introduction to the Gold Standard for Macromolecular Crystallography Diffraction Data
261 Study on structure, electrical and dielectric properties of pure and Sr-doped LaCoO3 for chemical sensor application.
262 X-ray fiber diffraction as a tool to study Nemaline Myopathy, a debilitating muscle disease
263 Macromolecular X-ray crystallography: soon to be a road less traveled?
264 Structural Basis for the tight binding inhibition of E coli. CTP Synthase Inhibition by Gemcitabine and its analogues
265 Structure of MlaFEDB lipid transporter reveals an ABC exporter fold and two bound phospholipids
271 The SHAPES Program for the Reconstruction of Protein Envelopes from X-ray Solution Scattering Data
272 Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase
273 Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase
274 Comprehensive strategy for quick determination of protein structures
276 MyD88 TIR domain signalosome interactions revealed by MicroED
277 Photocrystallographic studies of novel nickel (II) nitro complex supplemented by IR spectroscopy and multi-temperature XRD experiments
278 Recent advances in serial electron crystallography
279 Lessons learned from using the MiTeGen In Situ-1™ Crystallization Plate for microgravity protein crystallization
280 LabJack-like crystal structures of halogenated 2-phenylbenzimidazoles – are they isostructural?
281 The National School on Neutron and X-ray scattering (NX school) at Argonne and Oak Ridge National Lab
282 Partially Ordered Sets in Crystallography
283 Tracking solvent dynamics during carbonic anhydrase catalysis
284 Implementing Best Practices At The National Center For CryoEM Access And Training
285 Through-grid wicking enables high-speed cryoEM specimen preparation
286 Maximizing the value of cryoEM in drug discovery
287 High resolution cryo-EM structure of the EspA filament from EPEC: revealing the mechanism of effector translocation in the type 3 secretion system
288 High resolution cryo-EM structure of the EspA filament from EPEC: revealing the mechanism of effector translocation in the type 3 secretion system
289 Targeting Fe-S Protein to Fight Neglected Tropical Diseases
290 Cryo-EM and protein-protein docking reveal myosin loop 4 contacts actin and tropomyosin on thin filaments
291 Time-resolved serial femtosecond crystallography of the early intermediates in the isopenicillin N synthase reaction with ACV and O2
292 Towards Synergy of Macromolecular and Small Molecule Crystallography
293 A Portable Fixed-Target Sample Delivery System for in-situ Serial Crystallography
294 Pushing the Limits of Microfocus X-Ray Sealed Tube Sources for Biological and Chemical Crystallography
295 What's shaking? Molecular-dynamics simulations of X-ray diffraction from crystalline proteins.
296 Structural basis for the target specificity of actin histidine methyltransferase SETD3
297 Serial Electron Diffraction for Proteins and Small Molecules
298 Patient derived Fab structures suggest mechanism by which affinity maturation promotes autoantibody recognition of MuSK in the autoimmune disease myasthenia gravis
299 CryoDiscovery (TM): A machine learning platform for automated Cryogenic electron microscopy class average selection
300 CryoDRGN: a tool for reconstructing highly heterogeneous structural ensembles from cryo-electron micrographs
302 Small Molecule Microcrystal Electron Diffraction (MicroED) for the Pharmaceutical Industry
303 Determining Atomic Structures from Digitally Defined Regions of Nanocrystals
304 Structural Basis of the Interaction Between Ubiquitin Specific Protease 7 and Enhancer of Zeste Homolog 2
305 Broad HIV neutralization by a vaccine-induced cow antibody
306 Correction of the allosteric site of E. coli D-3-phosphoglycerate dehydrogenase
307 High-Pressure Structural and Equation of State Study of Atacamite, a Copper Hydroxychloride Mineral
308 New methods to capture insoluble, unstable titanium (IV) species in single-crystal form.
309 Structure of the human respiratory syncytial virus M2-1 protein in complex with a short positive-sense gene-end RNA
310 Toledo Crystallization Box: Microgravity Crystallization of Perdeuterated S. typhimurium Tryptophan Synthase for Neutron Diffraction
311 Undecided
313 Understanding the stoichiometric diversity and reactions of cocrystals through experimental and computational studies
314 Bacterial pseudokinase catalyzes protein polyglutamylation to inhibit the SidE-family ubiquitin ligases
315 Summer schools for magnetic crystallography and neutron diffraction
316 A bacterial surface layer protein exploits multistep crystallization for rapid self-assembly
317 How CRY Regulates the Clock: Structural Studies of a Dynamic Mammalian Circadian Complex
318 Structure of V-ATPase from mammalian brain
319 Translating hands-on activities to virtual resources for broader scientific engagement
322 Investigation of ATP-induced global motions of the human DNA mismatch repair sensor complex using time-lapse crystallography 
323 Structural characterization of different TRPA1 inhibitors
324 A Battleground with no Neutral Ground: Twitter for Scientists
325 Capturing Reaction Intermediates of the Water Oxidation Reaction In Photosystem II
326 Complementing high resolution structure methods with small angle X-ray scattering data.
327 Time-resolving biomolecular motions on length scales from single Å to Rg
329 Synthesis and characterization of metastable, crystalline st12 germanium
330 Structures of a dimodular nonribosomal peptide synthetase reveal conformational flexibility.
332 Real-time pressure-temperature reaction studies of biological systems using small-angle neutron scattering technique.
333 Direct detection of coupled proton and electron transfers in human manganese superoxide dismutase
334 Toledo Crystallization Box: Microgravity Crystallization of Perdeuterated S. typhimurium Tryptophan Synthase for Neutron Diffraction
335 HP-Bio: High Pressure BioSAXS for Deep Life and Extreme Biophysics
336 A Consensus Method to Prepare Crystal Structures in the Protein Data Bank for Downstream Applications
337 Single-particle cryo-EM studies of ERp44-ERAP1 and ERp44-ERAP2 reveal their ER-retention mechanism and structural dynamics involved
338 Incorporating HT-SAXS into Drug Discovery Pipelines
339 Finding Nearest Neighbors in Crystallography with NearTree
340 Understanding High-Pressure Formation of Topologically Non-trivial Intermetallic Compounds via In-Situ X-ray Diffraction
341 Cool structures from event-based single crystal neutron diffraction
342 Enhancing Protein Crystallization Screening Results Using Engineered Nucleation Features
343 Computationally directed discovery of bismuth based binary intermetallic materials
344 REGALS: data analysis at the SAS frontier
345 Toledo Crystallization Box: Microgravity Crystallization of Perdeuterated S. typhimurium Tryptophan Synthase for Neutron Diffraction
346 Structure of the Fiber Core of Orb2A, A Functional Amyloid, Revealed by Micro-electron Diffraction
347 Structure of an ALS/MSP-related D290V-mutation-containing hexapeptide in hnRNPA2 low-complexity domain reveals differences from its corresponding wild type peptide
348 Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20
350 A cryoEM and microED pipeline for the pharmaceutical and biotechnology industry
351 The Crystallization Transformations Sequence as Ice is Compressed at Low Temperature: Avoidance of Amorphization
352 The ISOTILT program for discovering cooperative rigid-unit modes (RUMs) in crystalline solids
353 Measurement of partial atomic charges by least-squares refinement of variable electron density crystallographic models.
354 Structural insights into enzymatic mechanism of methylenetetrahydrofolate reductase (MTHFR) from Sphingobium sp. SYK-6
356 Polymorph Evolution of Organic Molecules during Crystal Growth Studied by MicroED
357 Recent Developments SAXS using MetalJet X-ray Source
358 Utilizing Single-Crystal X-ray Diffraction to Determine Unusual Structural Trends within Group 15 Triamido Complexes
360 High Pressure Study on Novel Quantum Materials
362 _
363 Understanding c-di-GMP Signaling Specificity in Pseudomonas aeruginosa Pel-dependent Biofilms
365 Superconducting Superhydrides: Synthesis, Structure and Stability
366 Reinvestigation of the crystal structure of bis(3-aminopyridinium) tetrachloridocuprate(II)
367 Industrial CryoEM: reasons why and examples of impact
368 chameleon: Next Generation Sample Preparation for Cryo-EM
370 Mail-in and remote access for solution scattering at the LiX beamline
371 Evaluation of covalent bond density in molecular crystals using simplified virtual scattering centers: inorganic and complex compounds
372 Improved MicroED structures by cryo-FIB milling
373 MicroED on lipidic cubic phase embedded crystals
374 A cross-phase reaction coordinate in the formation of a mononuclear copper(II) orotate complex
375 Materializing Rival Ground States in the Barlowite Family of Kagome Magnets
376 Synthetic investigation on structure-property relationships in the Ca2-xMnxTi2O6 quadruple perovskite system
379 The SER-CAT Virtual Beamline: Providing light when YOU need it in your home lab
385 Discovery of an inhibitor of succinyl-CoA synthetase
386 A High Pressure Macromolecular Crystallography Capability Developed at CHESS
387 Structure-activity relationship analysis of mosquito glutathione S-transferase Noppera-bo and its inhibitors for insecticide development
388 Bimetallic platinum-based complexes: syntheses and synchrotron X-ray radiation structural studies
389 Bis(S-(-)-1-phenylethylammonium) tetrabromidocuprate(II): another step in the sequential breakdown of the A2CuX4 layer perovskite structure
390 Upconversion Enhancement via Functionalization of Plasmonic Nanoparticles
393 The crystal structure of gallic acid decarboxylase from Arxula adeninivorans
395 Crystal and Solution structures of Proliferating Cell Nuclear Antigen from Crenarchaeon Aeropyrum pernix
396 Investigation of Disease-causing Mutations in Sucrase-Isomaltase
397 Optimization of crystallization conditions for PfActII in complex with fragmin F1 domain
398 Structural basis for bisphosphonate-mediated inhibition of Leishmania major FPPS
399 Access modes to the highly automated BioSAXS beamline P12 of EMBL Hamburg
401 1,2-Cyclobutanecarboxylates Synthesized Using Photoreaction and Esterification
402 Targeting Protein Farnesyltransferase for Development of Antifungal Therapeutics
403 MicroED for small molecule and natural product research
404 B-factor analysis suggests that L-lysine and R, R-bisLysine allosterically inhibit Cj.DHDPS Enzyme by decreasing its protein dynamics
405 Structural study of phenylperimidines with potential applications as corrosion inhibitors
406 Optimal Box Size and Mask Diameter based on Defocus Distribution for Single Particle Cryo-EM
407 High-pressure Neutron Diffraction on WAND2in a Paris-Edinburgh Press
408 Structural study by X-ray diffraction of iron (III) complexes
409 Structural Studies of Manganese(III) Complex with Spin-Crossover and Thermochromic Properties
410 Using crystallographic models to experimentally measure partial atomic charges with comparison to quantum calculations
411 Direct and Simple Experimental Crystallographic Method to Calculate Partial Charges with Atomistic Correspondence to ab-initio Methods
412 Structural basis of Neisserial lactoferrin binding protein B function
413 DECOR: The Database of Educational Crystallographic Online Resources, Updates and Prospectus
414 Synthesis, Crystal Structures and Biomedical Application of Ferrocene-Hormone Complexes
415 FAD
417 test
418 Stanford-SLAC Cryo-EM Center
419 Electronic Structure and Site Dynamics in Copper Doped Tutton Salts
420 Application of neural networks for small angle scattering data analysis
421 The 1.9Å structure of PA5083 – a 116 residue protein with 1 ordered sulfur - determined by Native-SAD using in-house data and phenix.autobuild recycling.
422 Stanford-SLAC Cryo-EM Center
423 The 1.9Å structure of PA5083 – a 116 residue protein with 1 ordered sulfur - determined by Native-SAD using in-house data and phenix.autobuild recycling.
424 Structural basis of recognition of SARS-CoV-2 by neutralizing antibodies isolated from convalescent patients
425 Make MicroED an efficient tool for ultrahigh-resolution structural determination∠
426 Ternary alkali metal zinc antimonides and bismuthides: hydride synthesis and in-situ X-ray diffraction study
427 Structural insights into the feline coronavirus drug GC376, which inhibits the main protease of SARS-CoV-2 and blocks virus replication
430 Remote Opener: Breaking Barriers to Crystallization Using Remote Crystal Growth Screening and Imaging
431 If I had a trillion dollars
432 High-resolution crystal structures of recombinant wild type and selenomethione labeled bovine trypsin (S195A) mutant reveals no electron density for three surface loops that includes the C191 - C220 disulfide.
433 Structure-based Design of Prefusion-stabilized SARS-CoV-2 Spikes
434 Science at a distance: the CHESS experience
436 Advancing Structure-Based Drug Design: IMCA-CAT Responds to Emerging Needs of the Pharmaceutical Industry
437 Socially-distanced Crystallography in the time of COVID: Remote capabilities at SSRL
438 Microcrystal electron crystallographic analysis of organic solid solution (mixed crystal)
439 Online Crystallography: Fully Automated, Remote Controlled Protein-to-Structure Pipelines
440 Effects of chameleon dispense-to-plunge speed on particle concentration, complex formation, and final resolution: A case study using a bacterial ribonucleotide reductase
441 Structure and effector-binding analysis of a PreQ1-III riboswitch suggests a fold that is tolerant to binding pocket mutations.
442 Crystallography of SARS-CoV-2 Non-structural Proteins
443 A complete data processing workflow for in situ structure determination with cryo-electron tomography
444 Neural network particle picking and denoising in cryoEM with Topaz.
445 New developments in Scipion 3.0: consolidating the project as a collaborative software framework.
446 Single-particle cryo-EM at atomic resolution
447 Neural network particle picking and denoising in cryoEM with Topaz
449 Structural disorder and conformational flexibility in single particle cryo-EM
450 Understanding the evolution of SARS-CoV-2 non-structural protein 15 (Nsp15) in three dimensions (3D)
451 Mapping COVID-19 Mutations in 3D: How SARS-CoV-2 has evolved during the first 6 months of the global pandemic
452 Structural Analysis of Severe Acute Respiratory Syndrome Coronavirus-2 Proteins: Exploring Mutations in Nsp13
453 Delving Into COVID-19 “Seams”: Examining the Structural Fabric of SARS-CoV-2
455 Long range magnetic cooperativity through extended structural motifs? Introducing intermolecular - interactions into [3×3] Mn(II)9 and Cu(II)9 grids.
457 Optimal Box Size and Mask Diameter based on Defocus Distribution for Single Particle Cryo-EM
458 Lattice dynamics of antimony under pressure
459 High-resolution in situ imaging of biological samples with Warp and M
460 Crowdsourcing inhibitor discovery against the SARS-CoV-2 main protease
461 Protein Allostery
469 Crystal Structures of Large-Volume Commercial Pharmaceuticals
470 On the Completeness of Three-Dimensional Electron Diffraction Data for Structural Analysis of Metal-Organic Frameworks
472 Structural relationships between human transcriptional coactivators TFIID and SAGA
473 Integrating Chemical Crystallography into Undergraduate Laboratories: A Remotely Conducted Discovery Based Molecular Structure Determination Lab Module
474 Structural Characterization of a Hydroxyproline Dehydratase from C. difficile
475 Structurally investigating a niche pathway for chemical reversal of proline hydroxylation in the pathogen C. difficile
476 Diffraction and scattering studies using high brightness Excillum MetalJet X-ray sources
478 From integrative structural biology to cell biology
479 Methods to Trap High-Temperature Conformations of Proteins using Fast Cooling
480 Structures of Synthetic Nanobodies in Complex with SARS-CoV-2 Spike or Receptor-Binding Domain Provide Insights for Developing Therapeutics and Vaccines
481 Direct visualization of SARS-CoV-2 main protease electrostatics using neutron crystallography
482 Structural Analysis of a Zirconium Based Hydrogen Storage Material
484 Crystal Structure of a Zirconium Based Hydrogen Storage Material
485 test
486 Evaluation of the electrostatic potential, electric field and electric field gradient from the aspherical pseudoatom model in an infinite crystal.
487 Deploying high-throughput protein crystallography-based drug discovery platforms to establish a structure-based drug discovery system for SARS-CoV-2 proteins
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