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Structure based design of degraders.

Presented During:

Evolution and Impact of Targeted Protein Degradation in Industry  
08/05/2021: 12:35 PM - 1:00 PM
Virtual  

Conference:

2021: 71st ACA Annual Meeting

Session Type:

Oral Talk 

Presenting Author :

Radoslaw Nowak  
Dana-Farber Cancer Institute

Abstract Body:

Small molecule degraders have shown considerable promise as a new pharmacological modality. With the mounting structural information on degrader mediated ligase-substrate interactions we are beginning to understand the rationale for target recruitment and selectivity. This presentation will describe a structural basis for accelerating degrader design.

Additional Information - ORAL (2021)

Which session are you submitting your abstract to?

3.2.3 Evolution and Impact of Targeted Protein Degradation in Industry
3.2.3 Evolution and Impact of Targeted Protein Degradation in Industry