GENDER-AFFIRMING SURGERY ASSOCIATED WITH HIGH VIRAL SUPPRESSION AMONG TRANSGENDER PWH

Presented During:

Monday, Mar 8, 2021: 11:50 AM  - 12:00 PM 
Virtual CROI 2021  

Abstract Number:

107 

Abstract Type:

General Abstract  

Authors:

Cristina Rodriguez-Hart1, Gagarin Zhao1, Zil Goldstein2, Asa Radix2, Lucia Torian1

Institutions:

1New York City Department of Health and Mental Hygiene, Long Island City, NY, USA, 2Callen-Lorde Community Health Center, New York, NY, USA

Presenting Author:

Dr Cristina Rodriguez-Hart, PhD  

Background:

Although HIV surveillance contains information on HIV outcomes among transgender people with HIV (TPWH), it does not include other important data, e.g., gender-affirming care, which may impact HIV outcomes such as viral suppression (VS). 79% of NYC TPWH are enrolled in Medicaid, and recent policy changes have extended coverage for gender-affirming healthcare. We matched Medicaid data with the NYC HIV Registry to ascertain the association of gender-affirming surgery and VS.

Methods:

Because Medicaid claims do not specify transgender status, an algorithm using sex, diagnosis codes, and prescriptions was developed and applied to Medicaid claims from 2013-2017. This cohort was matched to the HIV Registry to identify which TPWH obtained gender-affirming surgery. We compared VS among TPWH in Medicaid who had surgery to TPWH who did not access Medicaid and cisgender women and men. We compared VS by type of surgery and examined trends in VS pre- and post-surgery.

Results:

We identified 6,335 transgender persons in Medicaid in 2013-2017, 1,764 (28%) of whom were TPWH. 185 (10%) TPWH in Medicaid had gender-affirming surgery. They had higher VS at last lab and the greatest increase in VS over the five years (86.5%, 8.9% increase) compared to TPWH who did not access Medicaid (78.6%, 7.5% increase), cisgender women (82.3%, 8.7% increase), and cisgender men (84.1%, 6.9% increase). Those who had "bottom" surgery had the highest proportion suppressed (89%) compared to other types of surgery. VS increased pre-surgery, at least in part due to the common practice requiring viral suppression prior to surgery, and remained high over time (66.3% 2 years prior, 76.9% 1 year prior, 86.3% 1 year after (among everyone), and 87.7% 2 years after (among those who had surgery prior to 2017)).

Conclusion:

Medicaid is a valuable source of data on transgender individuals and can complement data collected by HIV surveillance. While we cannot determine causality, it appears that preparing for gender-affirming surgery may be an important motivator in becoming virally suppressed. Moreover, it is associated with sustained high viral suppression, which is known to lead to improved survival and quality of life. Expanding Medicaid programs to include gender-affirming surgical care may be associated with better health outcomes among TPWH.

Epidemiology/Public Health:

(R) Epidemiology of HIV and SARS-CoV-2 in Adults

Keywords:

Gender affirming
Medicaid
Suppression
Transgender
Viral load

Supporting Image: Figureofviralsuppressionpreandpostsurgery121219.jpg
 

Does this abstract include any aspects of research on SARS-CoV-2 or COVID-19?

No

Prior Presentation or Publication: In general, CROI does not accept work that has been previously published or publicly presented. Abstract text that is under copyright by a publication or another conference should not be submitted verbatim to CROI. Consideration may be given to a previously presented submission if meaningful newer data or different analyses are included or if the prior presentation was to a conference not focused on HIV- or SARS-CoV-2-related topics. Have your study data or abstract information been published, submitted for publication where publication is anticipated on or before the start of the CROI where you will present, or presented at any other major national or international scientific or medical HIV-related conferences (ie, generally 400 or more attendees)?

No