PS72. The Effect of Smoking on Peri-operative, Post-operative, and Overall Survival After Robotic Assisted Pulmonary Resection

Emma Wong Poster Presenter
University of South Florida Morsani College of Medicine
Tampa, FL 
United States
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Emma Wong is a second-year medical student at the University of South Florida Health Morsani College of Medicine with a strong interest in thoracic surgery. Her research focuses on airway reconstruction outcomes, minimally invasive thoracic techniques, and socioeconomic disparities in surgical care. She conducts research under Dr. Eric Toloza at Moffitt Cancer Center and Dr. Erino Rendina and Dr. Beatrice Trabalza Marinucci at Sapienza University of Rome.

 

Saturday, May 6, 2023: 8:00 AM - Tuesday, May 9, 2023: 11:45 AM
Los Angeles Convention Center 
Room: Outside of Room 408 

Description

Objective: To analyze the effects of smoking on perioperative and postoperative outcomes of robotic-assisted lobectomy and segmentectomy in an NCI-designated cancer center.

Methods: Data was analyzed from 1,420 consecutive patients who underwent robotic-assisted segmentectomy (n=1,370) and lobectomy (n=50) performed by three different surgeons over a 12-year period. The perioperative, postoperative, and overall survival outcomes were compared between smoking patients (n=297) and non-smoking patients (n=1,123). The perioperative outcomes that were compared include estimated blood loss (cc), surgical duration (min), chest tube days, and hospital length of stay (LOS). Postoperative complications, 30-day mortality, and overall survival (OS) were also compared. Perioperative outcomes were compared between smoking and non-smoking groups using the student t-test. 5-year OS was compared using the log-rank test.

Results: There was a significant difference in preoperative FEV1% (p<0.0001) between smoking and non-smoking groups. Non-smoking patients had a greater mean FEV.1%. The smoking group had a significantly larger proportion of patients with chronic obstructive pulmonary disease compared to the non-smoking group (p<0.0001). The most significant differences in perioperative outcomes were chest tube duration (p<0.001) and total surgical duration (p=0.047), in which smoking patients experienced both longer chest tube duration and surgical duration. The remaining perioperative outcomes, 30-day mortality, and overall survival did not show any significant differences between both groups. The most significant differences in postoperative complications were prolonged air leak (p=0.025) and pneumonia (p=0.02), with smoking patients having a higher rate of incidence for both. Prolonged air leak was the most common complication in both smoking (67/297, 22.6%) and non-smoking patients (184/1,123, 16.4%). Pneumonia was the second most common complication in smoking patients (21/297, 7.1%).

Conclusion: The results indicate that smoking not only has a negative impact on preoperative FEV1%, but also on perioperative outcomes and postoperative complications in patients undergoing robotic-assisted pulmonary resections.

Presentation Duration

There is no formal oral presentation associated with this electronic poster. Your poster will be available for viewing at the poster kiosk located outside of the specialty room as well as in the Exhibit Hall, for the duration of the meeting. 

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