P241. Outcomes of Cardiovascular Surgery in Women with Turner Syndrome
McGovern Medical School at UTHealth
Houston, TX
United States - Contact Me
Avanced Aortic Surgery Fellow at Memorial Hermann Hospital, Houston.
I currently live in Houston, where I am completing a two- year Fellowship in advanced aortic surgery. I am greatly engaged in open surgery for aortic aneurysms and dissections, as well as in modern vascular surgery, with large interest in vascular innovations, latest technology in vascular and aortic endovascular surgery, and greatly interested in medical and academic education, as well as surgical simulation.
I previously joined La Fe University Hospital in 2014 as a junior physician in angiology and vascular surgery, within the department of vascular surgery.
Prior to La Fe, I was the first Spanish junior vascular surgeon to complete a senior clinical Fellowship in aortic surgery at St. Mary’s Hospital, Imperial College of London, during an 18- month period,
and one of the first Spanish surgeons to become an official fellow of the European board of vascular and endovascular surgery (FEBVS).
Prior to this experience, I completed my residency in vascular surgery at Gregorio Marañón University hospital in Madrid, during a five- year period.
During my tenure in Madrid, I helped the hospital with the medical and residents training program, and participated in several national and international simulation courses, workshops, and meetings.
I am a graduate of the University of Alcala in Madrid, where I majored my bachelor in medicine.
Description
To describe short- and mid-term surgical outcomes of patients with Turner syndrome (TS) after cardiovascular interventions.
Methods:
All individuals aged 18 years or older at the time of surgical repair for cardiovascular diseases, including coarctation repairs, aortic disease and aortic dissection, between 2002 and 2022 were eligible. The primary endpoint focused on complications or death within 30 days of surgery. Secondary outcomes encompassed late complications within 6 months. The analysis incorporated data from the University of Texas Health Science Center at Houston and the Turner Syndrome Society of the United States.
Results:
We identified 22 patients who met the inclusion criterion. The median age was 46 years (range, 21-75). The most common medical condition was hypertension (77%), followed by hypothyroidism (59%). The most frequent indication for surgery was aortic root or ascending aortic aneurysms (68%), followed by symptomatic aortic stenosis in patients with bicuspid aortic valve (64%), coarctation of aorta (45%), and acute aortic dissection (18%). Respiratory complications were the most common (68%). Pleural effusions were the most frequent found sign on imaging studies (68%). Thoracentesis, or chest tube placement, was required in 33% (5/15).
Conclusions:
Patients with TS may be at an increased risk for postoperative complications after aortic surgery. Bicuspid aortic valve (59%) and coarctation of the aorta (45%) were the most common congenital malformations among our study group. Our study showed that respiratory complications were the most common, with thoracentesis or chest tube placement required in 33% of patients. This is the largest series presenting mid-term outcomes of adult-only Turner syndrome patients following aortic surgery repair.
Authors
Lucas Ribe (1), Yuki Ikeno (1), Rana Afifi (2), Akiko Tanaka (3), Ferial Shihadeh (4), Anthony Estrera (3), Siddharth Prakash (5)
Institutions
(1) McGovern Medical School at UTHealth, Houston, TX, (2) Memorial Hermann, Houston, TX, (3) Memorial Hermann Heart and Vascular Institute, Houston, TX, (4) McGovern Medical School UTHealth, Houston, TX, (5) N/A, Houston, TX